Christine Garcia Roth, MD
Associate Professor of Pathology

Dr. Roth is the Co-Medical Director of the Clinical Flow Cytometry Laboratory and Director of the Hematopathology Core Residency Rotation.

Office Location:
Suite G300
UPMC-PUH
200 Lothrop Street
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-647-5191
Fax: 412-647-0374
Email: garciac@upmc.edu

Education

  • MD - Baylor College of Medicine, 2001
  • BA - Rice University , 1996

Certifications

  • Diplomate, American Board of Pathology, Anatomic and Clinical Pathology, 2006
  • Diplomate, American Board of Pathology, Specialty Certification in Hematology 2007
  • Diplomate, American Board of Pathology, Recertification in AP/CP/Hematology 2014

Specialties

Hematopathology

Clinical Expertise

Dr. Roth's expertise is in hematopathology, including bone marrow and lymph node pathology, and application of flow cytometric, immunohistochemical, cytogenetic, and molecular studies in clinical diagnosis.

Research Expertise

Pathobiology and classification of hematopoietic disorders, including neoplastic and non-neoplastic myeloid and lymphoid processes. Recent and ongoing projects include: Identification of biomarkers useful in the diagnosis and subclassification of reactive and neoplastic myeloid and lymphoid processes, characterization of benign and malignant breast lymphoplasmacytic proliferations, and clinicopathologic features of early precursor T-lymphoblastic leukemia.

Awards and Honors

  • Co-Director, "The Virtual Pathology Instructor" - awarded a 2012 Innovation in Education grant from the University of Pittsburgh Provost's Advisory Council on Instructional Excellence (ACIE)
  • Nominated for Outstanding Clinical Pathology Teaching Award, 2014, 2012

Selected Publications

View Dr. Roth's publications on PubMed

  • Berg A, Soma L, Clark BZ, Swerdlow SH, Roth CG. Evaluating breast lymphoplasmacytic infiltrates: a multiparameter immunohistochemical study, including assessment of IgG4. Human Pathology 2015 Apr 28 [Epub ahead of print]
  • Hellman C, Marcogliese AN, Djokic M, Roth CG. CD123 immunohistochemical expression is a specific but insensitive marker of early T-precursor leukemia. Applied Immunohistochemistry and Molecular Morphology 2015 Apr 21 [Epub ahead of print]
  • Craig FE, McGee JB, Mahoney JF, Roth CG. The Virtual Pathology Instructor (V-PIN): A medical student teaching tool developed using patient simulator software. Human Pathology. 2014: 45(10) 1985 - 94.
  • Garner K, Ten Eyck S, Craig FE, Roth CG. TIM3 is underexpressed on myeloblasts in untreated myelodysplastic syndrome. Leukemia Lymphoma. 2014; 55(3) 689-91.
  • Chen ZW, Kotsikogianni I, Raval J, Roth C, Rollins-Raval MA. Biclonal IgD and IgM Plasma Cell Myeloma: Report of two cases and review of the literature. Case Reports in Hematology 2013: 293150 [Epub Nov 18]
  • Roth CG, Garner K, Ten Eyck S, Boyiadzis M, Kane LP, Craig FE. TIM3 expression on normal and leukemic myeloblasts. Cytometry B Clin Cytom 2013; 84(3):167-72.
  • Courville E, Wu Y, Kourda J, Roth CG, Brockmann J, Muzikansky A, Fathi AT, de Leval L, Orazi A, Hasserjian RP. Clinicopathologic analysis of acute myeloid leukemia arising from chronic myelomonocytic leukemia. Modern Pathology 2013; 26(6): 751-61.
  • Rollins-Raval MA, Marafioti T, Swerdlow SH, Roth CG. The number and growth pattern of plasmacytoid dendritic cells vary in different types of reactive lymph nodes: an immunohistochemical study. Human Pathology. 2013; 44(6): 1003-10.
  • Rollins-Raval MA, Pillai R, Warita K, Mitsuhashi-Warita T, Mehta R, Djokic M, Kant JA, Roth CG. CD123 immunohistochemical expression in acute myeloid leukemia is associated with underlying FLT3-ITD and NPM1 mutations. Applied Immunohistochemistry and Molecular Morphology. 2013; 21(3): 212-7.