Jianmin Tian, PhD
Research Assistant Professor of Pathology
Dr. Tian is a member of the Division of Experimental Pathology.
University of Pittsburgh
Department of Pathology
200 Lothrop St, Room BSTS426
Pittsburgh, PA 15261
Office Telephone: 412-648-9656
- PhD - University of Geneva, Switzerland
Research InterestsTranscriptional regulations in liver cancer
Selected PublicationsHarris, T., Pan, Q., Sironi, J., Lutz, D., Tian, J., Sapkar, J., Perez-Soler, R., Keller, S., Locker, J. (2011). Both gene amplification and allelic loss occur at 14q13.3 in lung cancer. Clin Cancer Res. 17(4): 690íV699.
Tian J, Huang H, Hoffman B, Liebermann DA, Ledda-Columbano GM, Columbano A, Locker J. (2011) Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in mice. J Clin Invest. 121(11):4491-502
Tian, J., Mahmood, R., Hnasko, R., Kajiyama, Y., and Locker, J.(2006) Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia. Cancer Res. 66, 10399-407.
Kajiyama Y. Tian J., and Locker J. (2006) Organization of distant enhancers and their promoter interactions are independent of repression. J. Biol. Chem. 281, 30122-31
Columbano, A., Ledda-Columbano, G.M., Pibiri, M., Cossu, C., Menegazzi, M., Moore, D.D., Huang, W., Tian, J., and Locker, J. (2005) Gadd45β is induced through a CAR-dependent TNF-independent pathway in liver hyperplasia. Hepatology 42, 1118-26.
Locker J., Tian J., Carver R., Concas D., Cossu C., Ledda-Columbano G. M. and Columbano A. (2003) A Common Set of Immediate-Early Response Genes in Liver Regeneration and Hyperplasia. Hepatology 38, 314-325.
Kajiyama Y., Tian J. and Locker J. (2002) Regulation of α-fetoprotein expression by Nkx2.8. Mol. Cell. Biol. 22: 6122-6130.