Shirish Paranjpe, PhD
Research Assistant Professor of Pathology

Dr. Paranjpe is a member of the Division of Experimental Pathology.
Office Location:
Rm. S412 SBST
Department of Pathology
200 Lothrop St.
Pittsburgh, PA 15261
Contact Information:
Office Telephone: 412-383-8787
Fax: 412-648-1916

Research Interests

  1. Inhibition of c-Met and EGFR in Rodents and its effect on liver Regeneration.
  2. Investigation of the role of Decorin in Liver Biology.
  3. MicroRNA Expression Profiles in Regenerating Rat liver.

Selected Publications

View Dr. Paranjpe's publications on PubMed

Lin Chih-Wen; Mars Wendy M.; Paranjpe S; et al. Hepatocyte Proliferation and Hepatomegaly Induced by Phenobarbital and 1,4-Bis [2-(3,5-Dichloropyridyloxy)] Benzene Is Suppressed in Hepatocyte-Targeted Glypican 3 Transgenic Mice. Hepatology, 2011, 54: 620-630.

Bhave VS, Paranjpe S, Bowen WC, Donthamsetty S, Bell AW, Khillan JS, Michalopoulos GK. Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo. Hepatology. 2011 Jul 7. doi: 10.1002/hep.24507. [Epub ahead of print].

Paranjpe S, Bowen WC, Tseng GC, Luo, J-H, Orr, A & Michalopoulos, GK. RNA Interference against hepatic Epidermal Growth Factor Receptor has Suppressive Effects on Liver Regeneration in Rats. Am J Pathol. 2010, 176:2669-2681.

Liu B, Bell AW, Paranjpe S, Bowen WC, Khillan JS, Luo J-H, Mars WM, Michalopoulos GK. Suppression of Liver Regeneration & Hepatocyte Proliferation in Glypican 3 Hepatocyte -Targeted Transgenic Mice. In Press, Hepatology 2010.

Liu B, Paranjpe S, Bowen WC, Bell AW, Luo JH, Yu YP, Mars WM, Michalopoulos GK. Investigation of the Role of Glypican 3 in Liver Regeneration and Hepatocyte Proliferation. Am J Pathol. 2009, 175:717-724.

Paranjpe S, William C. Bowen, Aaron W. Bell, Kari Nejak-Bowen, Luo,J-H & George K. Michalopoulos. Cell Cycle Effects resulting from inhibition of HGF and its receptor c-met in regenerating rat liver by RNA interference. Hepatology. 2007 45 (6): 1471-1477.